The protein carriers of hundreds of lipids have been identified

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But that still amounted to about 40,000 people.

What if you create a truly unique routing profile that's wildly different from the common ones for which shortcuts were pre-calculated? The system is smart. If it detects that too many shortcuts (~50, for example) need on-the-fly recalculation and deviate significantly, it might determine that falling back to the original, comprehensive A* algorithm for the entire route would actually be faster than doing many small, heavily modified A* calculations.

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